Evaluation of antioxidant and α-glucosidase inhibitory activity of green tea powder from Indonesian tea cultivars

Trinovani, Elvi and Iqbal Prawira-Atmaja, Mukhammad and Kusmiyati, Mimin and Shabr, Shabri (2025) Evaluation of antioxidant and α-glucosidase inhibitory activity of green tea powder from Indonesian tea cultivars. Beverage Plant Research, 5 (e005). pp. 1-8. ISSN 2769-2108

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Abstract

The enzyme α-glucosidase plays a crucial role in the digestive system by hydrolyzing carbohydrates to produce absorbable glucose. With the recent surge in
the popularity of green tea powder (GTP) in Indonesia, this study aims to determine the potential of GTP derived from Indonesian tea cultivars as sources of
antioxidants and inhibitors of α-glucosidase activity. Four Indonesian tea cultivars ('GMB-3', 'GMB-7', 'GMB-9', and 'GMBS-4') were utilized to produce green
tea powder, following which their physicochemical properties, antioxidant activity, and α-glucosidase inhibition activity were evaluated. The results
revealed that GTP has particle size at d50 ranging from 1.03 to 1.96 μm with total polyphenol content of GTP ranging from 244.57 to 277.91 mg GAE/g.
Notably, the 'GMBS-4' cultivar produced GTP with the highest total flavonoid content (223.52 mg QE/g), the lowest IC50 (12.27 mg/L), and exhibited the
highest α-glucosidase inhibitory activity (42.54%). Furthermore, the GTP derived from the 'GMB-3' cultivar exhibited a higher total catechin content (4.39%)
compared to the other cultivars. The inhibition of α-glucosidase activity of GTP ranged from 30% to 42% at a concentration of 500 μg/mL. These findings
suggest that Indonesian green tea powder exhibits α-glucosidase inhibitor activity, although at a concentration higher than acarbose. However, Indonesian
tea cultivars demonstrate promising potential for producing green tea powder with antioxidant properties and α-glucosidase inhibitors. Therefore, further
research and development of Indonesian tea cultivars are expected to improve GTP quality in Indonesia.

Item Type:	Article
Subjects:	600 Teknologi dan Ilmu-ilmu Terapan > 610 - 619 Ilmu Kedokteran dan Ilmu Pengobatan 600 Teknologi dan Ilmu-ilmu Terapan > 610 - 619 Ilmu Kedokteran dan Ilmu Pengobatan > 615.4 Farmasi Praktis
Divisions:	Jurusan Farmasi > D III
Depositing User:	Miss Elvi Trinovani
Date Deposited:	08 Oct 2025 02:44
Last Modified:	08 Oct 2025 02:44
URI:	http://repo.poltekkesbandung.ac.id/id/eprint/13484

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